What it is
Nausea and vomiting describe the subjective sensation of the urge to vomit and the reflex expulsion of gastric contents — among the most common presenting symptoms in clinical medicine.
The sensation of impending vomiting and the forceful expulsion of stomach contents — occurring across a wide spectrum of causes from pregnancy to serious systemic disease.

At a glance
What it is
Nausea and vomiting describe the subjective sensation of the urge to vomit and the reflex expulsion of gastric contents — among the most common presenting symptoms in clinical medicine.
Commonly experienced as
Evidence context
Research-supportedSee the evidence snapshotSafety
See staying safeContext
Nausea is the subjective sensation of the urge to vomit, typically accompanied by autonomic features (pallor, sweating, salivation, tachycardia). Vomiting is the reflex contraction of the abdominal muscles and diaphragm forcefully expelling gastric contents. Together they are among the most commonly experienced and presenting symptoms across all clinical settings. Causes span the gastrointestinal (gastroenteritis, gastro-oesophageal reflux, peptic ulcer, gastroparesis, IBD), neurological (migraine, vestibular — motion sickness, labyrinthitis, Ménière's disease; raised intracranial pressure), endocrine/metabolic (pregnancy, diabetic ketoacidosis, hypercalcaemia, Addison's disease), drug/toxin-related (chemotherapy, NSAIDs, opioids, alcohol, digoxin), and psychiatric (eating disorders, anxiety, functional nausea). The temporal pattern — acute, cyclic, or chronic — combined with associated symptoms guides differential diagnosis.
The Evidence
What research and clinical practice tell us about nausea and vomiting — causes, management options, and when to seek urgent care.
Well-studied symptom with clear management pathways
Nausea and vomiting are among the most researched symptoms in medicine, with strong evidence supporting both conventional antiemetics and select complementary approaches such as ginger and acupressure. Identifying the underlying cause is essential to appropriate management.
Seek emergency care for blood in vomit, vomiting alongside severe headache with neck stiffness or light sensitivity, severe abdominal pain with rigidity, or vomiting with confusion. These may indicate serious conditions including GI bleeding, meningitis, bowel obstruction, or a metabolic emergency. Do not delay assessment.
Antiemetics such as ondansetron, metoclopramide, and prochlorperazine are well-evidenced for acute nausea. Structured antiemetic regimens are standard for chemotherapy-related nausea. Ginger (around 1 g daily) has consistent evidence for pregnancy-related nausea and chemotherapy nausea. Acupressure at the P6 wrist point has moderate evidence across multiple nausea types.
Metoclopramide should not be used long-term due to risk of tardive dyskinesia, and is not appropriate where bowel obstruction is suspected. Ondansetron may prolong the QT interval — relevant for those with heart conditions or taking other QT-affecting medications. Always discuss medication choices with a qualified health professional.
Ginger is used across Ayurveda, Traditional Chinese Medicine, and European herbal traditions for nausea — and is one of the few traditional remedies with consistent clinical evidence. Acupressure at the P6 (Nei Guan) point is widely used and has research support. Peppermint and fennel are common traditional remedies, though evidence is more limited.
Causes include gastrointestinal infections, pregnancy, migraine, vestibular disorders, medication side effects, and metabolic conditions such as diabetic ketoacidosis. The pattern — whether acute, cyclic, or chronic — and associated symptoms help guide assessment. Identifying the cause shapes which management approach is most appropriate.
Nausea lasting more than a few days, recurring without clear cause, or accompanied by weight loss, difficulty swallowing, or other concerning features should be assessed by a qualified health professional. Self-management is appropriate for mild, short-lived cases — but professional assessment is important when the cause is unclear or symptoms are severe.
Safety first
General, informational guidance — not diagnostic. A qualified practitioner can advise on your own situation.
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