Negative Mood Changes
A sustained or episodic deterioration in mood characterised by irritability, sadness, anxiety, or emotional flatness. Negative mood changes can be a symptom of many physical and psychological conditions, or arise from lifestyle and environmental factors.
Quick answer
Negative mood changes (ICD-10: R45.1; ICD-11: MB20) span irritability, sadness, and emotional flatness. Common across depression, PMS/PMDD, thyroid dysfunction, and burnout. Exercise, omega-3, and CBT have strong evidence. Hormonal drivers require targeted assessment.
Recognition
Do any of these feel familiar?
Persistent low, sad, or irritable mood
Increased emotional reactivity or tearfulness
Loss of emotional resilience or ability to recover from minor setbacks
Withdrawal from social engagement
Feeling of heaviness, bleakness, or emotional difficulty
What is Negative Mood Changes?
A sustained or episodic deterioration in mood characterised by irritability, sadness, anxiety, or emotional flatness. Negative mood changes can be a symptom of many physical and psychological conditions, or arise from lifestyle and environmental factors.
Approaches Commonly Explored
Commonly explored for conditions related to Negative Mood Changes, grouped by mechanism — select your subtype above to highlight the most relevant path.
How to use these approaches
Most people begin with Stabilise approaches, then progress toward Resolve and Sustain.
Cognitive patterns, emotional processing, and stress response.
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